Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

ABSTRACT

Solubility of 2-isopropylimidazole in nine organic solvents including methanol, ethanol, n-propanol, isopropanol, acetone, acetonitrile, ethyl acetate, toluene, 2-butanone and liquid mixture of (methanol + ethyl acetate) were determined experimentally by using the isothermal saturation method over the temperature range from (278.15 to 313.15) K under atmosphere pressure (101.2 kPa). The solubility of 2-isopropylimidazole in the pure solvents increased with a rise of temperature. In general, the mole fraction solubility obeyed the following order from high to low in different pure solvents: methanol greater than ethanol greater than 2-butanone greater than n-propanol greater than acetone greater than isopropanol greater than ethyl acetate greater than acetonitrile greater than toluene. For the (methanol + ethyl acetate) mixture with given initial composition, the mole fraction solubility of 2- isopropylimidazole increase with increasing temperature and mass fraction of methanol. The obtained solubility of 2-isopropylimidazole in the pure solvents was correlated with the modified Apelblat equation and kh equation; and in the binary solvent mixture, the Jouyban Acree model, van t Hoff Jouyban Acree model and modified Apelblat Jouyban Acree model. The maximum values of root-mean-square deviation (RMSD) and relative average deviation (RAD) were 19.2*10-3 and 1.07%, respectively. In addition, the standard dissolution enthalpy was calculated.