ABSTRACT

Amino acids are the building blocks of proteins and their study provides important information, which can be related to the behavior of larger biomolecules such as proteins. The present article reports experimental values of density (q) and speed of sound (u) of aqueous binary mixtures of biologically important amino acid derivatives, namely, L-alanine methyl ester hydrochloride and L-valine methyl ester hydrochloride at different temperatures i.e. T = (278.15, 288.15 and 298.15) K within the concentration range of (0-0.16) mol kg-1. The obtained data of densities and speeds of sound of solutions were processed to obtain different derived parameters, such as apparent molar volume of solute, isentropic compressibility of solution and apparent molar isentropic compressibility of solute. The limiting values of apparent molar volume of solute, apparent molar isentropic compressibility of solute, apparent molar expansivity of solute, coefficient of thermal expansion, hydration number and second derivative of limiting apparent molar volume have also been computed. The results have been interpreted in terms of various interactions occurring among solute and solvent molecules and structure making and structure breaking tendencies of the solute in these aqueous binary systems.

Compounds

#	Formula	Name
1	C4H10ClNO2	methyl L-alaninate hydrochloride
2	C6H14ClNO2	methyl L-valinate hydrochloride
3	H2O	water

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1 3	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	Pycnometric method	13
POMD	1 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	26
POMD	1 3	Speed of sound, m/s ; Liquid	Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Temperature, K; Liquid Frequency, MHz; Liquid	Liquid	Linear variable-path acoustic interferometer	13
POMD	1 3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	26
POMD	2 3	Mass density, kg/m3 ; Liquid	Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	Pycnometric method	13
POMD	2 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	26
POMD	2 3	Speed of sound, m/s ; Liquid	Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid Temperature, K; Liquid Frequency, MHz; Liquid	Liquid	Linear variable-path acoustic interferometer	13
POMD	2 3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	26

Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Physicochemical study of solute-solute and solute-solvent interactions of aqueous binary mixtures of L-alanine methyl ester hydrochloride and L-valine methyl ester hydrochloride at different temperatures: Volumetric and compressional studies

Dhondge, S. S.[Sudhakar S.], Moses, J. M.[Jessie M.], Deshmukh, D. W.[Dinesh W.], Paliwal, L. J.[Lalitmohan J.], Tangde, V. M.[Vijay. M.], Dhondge, A. S.[Alka S.]

ABSTRACT