ABSTRACT

Sound speeds have been measured for aqueous solutions of six tripeptides of sequence glycyl-X-glycine, where X is one of the amino acids glycine, alanine, leucine, asparagine, threonine, and tyrosine at T = 298.15 K and at the pressures p = (10, 20, 40, 60, 80, 100, and 120) MPa. Using methods described in previous work, these sound speeds were used to derive the partial molar volumes at infinite dilution, V2 o, the partial molar isentropic compressions at infinite dilution, KS,2 o , and the partial molar isothermal compressions at infinite dilution, Ko T,2 {Ko T,2 = (dV2o/dp)T}, for the tripeptides in aqueous solution at the elevated pressures. The results were used to calculate the partial molar volumes and partial molar isothermal compressions for the various amino acid side-chains over the pressure range p = (10-120) MPa.

Compounds

#	Formula	Name
1	C6H11N3O4	glycylglycylglycine
2	C7H13N3O4	glycylalanylglycine
3	C10H19N3O4	glycyl-L-leucylglycine
4	C8H14N4O5	glycyl-L-asparaginylglycine
5	C8H15N3O5	glycyl-L-threonylglycine
6	C13H17N3O5	glycyl-L-tyrosylglycine
7	H2O	water

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1 7	Speed of sound, m/s ; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 1; Liquid	Temperature, K; Liquid Frequency, MHz; Liquid	Liquid	Single path-length method	42
POMD	7 2	Speed of sound, m/s ; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 2; Liquid	Temperature, K; Liquid Frequency, MHz; Liquid	Liquid	Single path-length method	42
POMD	3 7	Speed of sound, m/s ; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 3; Liquid	Temperature, K; Liquid Frequency, MHz; Liquid	Liquid	Single path-length method	42
POMD	7 4	Speed of sound, m/s ; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 4; Liquid	Temperature, K; Liquid Frequency, MHz; Liquid	Liquid	Single path-length method	33
POMD	7 5	Speed of sound, m/s ; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 5; Liquid	Temperature, K; Liquid Frequency, MHz; Liquid	Liquid	Single path-length method	42
POMD	6 7	Speed of sound, m/s ; Liquid	Pressure, kPa; Liquid Molality, mol/kg - 6; Liquid	Temperature, K; Liquid Frequency, MHz; Liquid	Liquid	Single path-length method	42

Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Thermodynamic properties of peptide solutions 20. Partial molar volumes and isothermal compressions for some tripeptides of sequence gly-X-gly (X = gly, ala, leu, asn, thr, and tyr) in aqueous solution at T = 298.15 K and p = (10-120) MPa

Hedwig, G. R.[Gavin R.], Hoiland, H.[Harald]

ABSTRACT