ABSTRACT

Viscosity, g and enthalpy of dilution, q of studied nucleic acid bases (uracil, cytosine, thymine) and nucleosides (uridine, cytidine and thymidine) in water and in aqueous solutions of (0.10, 0.25, 0.50, 0.75 and 1.00) mol kg 1 guanidine hydrochloride (GnHCl) have been determined over a temperature range (288.15-318.15) K at (101.3 +- 0.5) kPa. These data have been used to calculate viscosity B-coefficients and standard molar enthalpy of dilution, DdilHo which have further been used to evaluate corresponding transfer parameters DtrB and DtrDdilHo, respectively. Positive DtrB values and negative DtrDdilHo values indicate the predominance of hydrophilic ionic interactions in these systems. Temperature dependence of B-coefficient and DdilHo has also been discussed. Spectroscopic studies have been carried out to further investigate the structural changes and the interactions involved in the mixed aqueous solutions.

Compounds

#	Formula	Name
1	C4H4N2O2	2,4(1H,3H)-pyrimidinedione
2	C4H5N3O	4-amino-2-hydroxypyrimidine
3	C5H6N2O2	thymine
4	C9H12N2O6	uridine
5	C9H13N3O5	cytidine
6	C10H14N2O5	thymidine
7	CH6ClN3	guanidine hydrochloride
8	H2O	water

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	4
POMD	7 1 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 7; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	168
POMD	7 2 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 7; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	168
POMD	7 3 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 7; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	168
POMD	7 4 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 7; Liquid Molality, mol/kg - 4; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	168
POMD	7 5 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 7; Liquid Molality, mol/kg - 5; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	168
POMD	7 6 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 7; Liquid Molality, mol/kg - 6; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	168
POMD	1 8	Molar enthalpy of dilution, kJ/mol ; Liquid	Temperature, K; Liquid	Initial molality of solute, mol/kg; Liquid Pressure, kPa; Liquid Final molality of solute, mol/kg; Liquid	Liquid	Calvet calorimetry	4
POMD	1 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	24
POMD	7 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 7; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	20
POMD	2 8	Molar enthalpy of dilution, kJ/mol ; Liquid	Temperature, K; Liquid	Initial molality of solute, mol/kg; Liquid Pressure, kPa; Liquid Final molality of solute, mol/kg; Liquid	Liquid	Calvet calorimetry	4
POMD	2 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	24
POMD	3 8	Molar enthalpy of dilution, kJ/mol ; Liquid	Temperature, K; Liquid	Initial molality of solute, mol/kg; Liquid Pressure, kPa; Liquid Final molality of solute, mol/kg; Liquid	Liquid	Calvet calorimetry	4
POMD	3 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	24
POMD	4 8	Molar enthalpy of dilution, kJ/mol ; Liquid	Temperature, K; Liquid	Initial molality of solute, mol/kg; Liquid Pressure, kPa; Liquid Final molality of solute, mol/kg; Liquid	Liquid	Calvet calorimetry	4
POMD	4 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 4; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	24
POMD	5 8	Molar enthalpy of dilution, kJ/mol ; Liquid	Temperature, K; Liquid	Initial molality of solute, mol/kg; Liquid Pressure, kPa; Liquid Final molality of solute, mol/kg; Liquid	Liquid	Calvet calorimetry	4
POMD	5 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 5; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	24
POMD	6 8	Molar enthalpy of dilution, kJ/mol ; Liquid	Temperature, K; Liquid	Initial molality of solute, mol/kg; Liquid Pressure, kPa; Liquid Final molality of solute, mol/kg; Liquid	Liquid	Calvet calorimetry	4
POMD	6 8	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 6; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	24

Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Solvation behavior of some nucleic acid bases and nucleosides in water and in aqueous guanidine hydrochloride solutions: Viscometric, calorimetric and spectroscopic approach

Banipal, T. S.[Tarlok S.], Kaur, N.[Navalpreet], Banipal, P. K.[Parampaul K.]

ABSTRACT