This paper describes the results of thermodynamic study of dissolution of proto- and mesoporphyrins in liquid N,N-dimethylformamide (DMF) at different temperatures. Enthalpies of solution and solubility of protoporphyrin dimethylester (PDE) and mesoporphyrin dimethylester (MDE) in DMF have been obtained from T = (298 to 318) K. Free energies, enthalpies, entropies and heat capacities of solution have been computed from the combination of enthalpic and solubility data via the Gibbs Helmholtz equation. We have shown that for all blood porphyrins this approach reproduces both free energies of solution and solubility values for the physiological temperature range.
Compounds
#
Formula
Name
1
C36H38N4O4
protoporphyrin IX, dimethyl ester
2
C36H42N4O4
mesoporphyrin, dimethyl ester
3
C3H7NO
dimethylformamide
Datasets
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.