Thermodynamic models for determination of the solubility of DL-malic acid in methanol plus (acetonitrile, N,N-dimethylformamide, isopropyl alcohol) binary solvent mixtures
The solubility of DL-malic acid in binary solvent mixtures consisting of (methanol + acetonitrile); (methanol + N,N-dimethylformamide); and (methanol + isopropyl alcohol) was measured at temperatures ranging from (278.15 to 328.15) K by gravimetric method. Values of the solubility were fitted using modified Apelblat equation and Buchowski Ksiazaczak kh model. Computational results showed that the modified Apelblat equation was superior to the other equation. In addition, the thermodynamic properties of the solution process, including the Gibbs free energy, enthalpy, and entropy were calculated by the van t Hoff analysis. This study provides valuable data for the DL-malic acid purification by the preferential crystallization procedure.
Compounds
#
Formula
Name
1
C4H6O5
hydroxybutanedioic acid
2
CH4O
methanol
3
C2H3N
acetonitrile
4
C3H7NO
dimethylformamide
5
C3H8O
propan-2-ol
Datasets
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.