Data on (solid + liquid) equilibrium of tylosin tartrate in {methanol + (ethanol, 1-propanol or 2-propanol)} solvents will provide essential support for industrial design and further theoretical studies. In this study, the solubility of tylosin tartrate in alcohol mixtures was measured over temperature range from (278.15 to 323.15) K under atmospheric pressure by a gravimetric method. From the experimental results, the solubility of tylosin tartrate in selected solvents noted above was found to increase with increasing temperature and mass fraction of methanol. The solubility data were correlated with the modified Apelblat equation, the kh equation and van t Hoff equation. The results showed that the three equations agreed well with the experimental values, and that the modified Apelblat equation was more accurate than the kh equation and van t Hoff equation. Further, the standard enthalpy, standard entropy and standard Gibbs free energy of solution of tylosin tartrate in mixed solvents were calculated according to solubility results, model parameters with modified Apelblat equation and van t Hoff equation.
Compounds
#
Formula
Name
1
C50H83NO23
tylosin tartrate
2
CH4O
methanol
3
C2H6O
ethanol
4
C3H8O
propan-1-ol
5
C3H8O
propan-2-ol
Datasets
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.