ABSTRACT

The densities (q) and speeds of sound (u) of betaine hydrochloride (B.HCl) drug (0.01 to 0.06) mol kg 1 in (0.10, 0.20 and 0.30) mol kg 1 aqueous D(+)-glucose and sucrose solutions are reported as a function of temperature at T = (293.15 to 313.15) K and atmospheric pressure. The values of density (q) and speed of sound (u) are obtained with high precision. These values have been used to estimate the apparent molar volume (V2,/), partial molar volume (V12 ), transfer partial molar volume (DtV12 ), apparent molar isentropic compressibility (Ks,2,/), partial molar isentropic compressibility (K1s ;2), transfer partial molar compressibility (DtK1s ;2), hydration number (NH), partial molar expansion (E12 ) and Hepler s constant (d2V2 /dT2)P. Furthermore, pair (VAB and KAB) and triplet (VABB and KABB) interaction coefficients have been computed from the values of DtV12 and DtK1s ;2. The co-sphere overlap model is used to understand the values of DtV12 and DtK1s ;2. The positive values of (d2V2 /dT2)P indicate structure making ability of betaine hydrochloride in aqueous D(+)-glucose and sucrose solutions at the temperatures and compositions investigated.

Compounds

#	Formula	Name
1	C5H12ClNO2	betaine hydrochloride
2	C6H12O6	D-glucose
3	C12H22O11	D-sucrose
4	H2O	water

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	5
POMD	4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	5
POMD	2 1 4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 2; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	140
POMD	2 1 4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 2; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	140
POMD	3 1 4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 3; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	140
POMD	3 1 4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Solvent: Molality, mol/kg - 3; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	140
POMD	2 4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	15
POMD	2 4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 2; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	15
POMD	1 4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	30
POMD	1 4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 1; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	30
POMD	3 4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	15
POMD	3 4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid Molality, mol/kg - 3; Liquid	Pressure, kPa; Liquid Frequency, MHz; Liquid	Liquid	Sing-around technique in a fixed-path interferometer	15

Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Acoustic and volumetric properties of betaine hydrochloride drug in aqueous D(+)-glucose and sucrose solutions

Ryshetti, S.[Suresh], Gupta, A.[Akash], Tangeda, S. J.[Savitha Jyostna], Gardas, R. L.[Ramesh L.]

ABSTRACT