ABSTRACT

The calorimetric measurements of solution enthalpy of a-cyclodextrin, b-cyclodextrin in water (H2O), dimetyloformamid (DMF), dimethyl sulfoxide (DMSO) and aqueous ethanol solutions (H2O + EtOH) at 298.15 K were made. The experimental results were used to calculate the enthalpic coefficients of the interactions between cyclodextrin and ethanol molecules in water based on McMillan Mayer s model. The results were compared with literature data and with hydrodynamic radii of cyclodextrin in examined solvents and with donor numbers of these solvents. In order to check, if the inclusion complex formation between the solvent with the highest enthalpy of solution and cyclodextrin has happened, the calorimetric isothermal titration measurements were made and the results were interpreted.

Compounds

#	Formula	Name
1	C3H7NO	dimethylformamide
2	C2H6OS	dimethyl sulfoxide
3	C2H6O	ethanol
4	C36H60O30	.alpha.-cyclodextrin
5	C42H70O35	.beta.-cyclodextrin
6	H2O	water
7	CH4N2O	urea
8	C2H5NO2	2-aminoacetic acid

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	6 4	Molar enthalpy of solution, kJ/mol ; Liquid	Molality, mol/kg - 4; Liquid	Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	ISOPERIBOL	8
POMD	5 6	Molar enthalpy of solution, kJ/mol ; Liquid	Molality, mol/kg - 5; Liquid	Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	ISOPERIBOL	8
POMD	1 5	Molar enthalpy of solution, kJ/mol ; Liquid	Molality, mol/kg - 5; Liquid	Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	ISOPERIBOL	8
POMD	2 5	Molar enthalpy of solution, kJ/mol ; Liquid	Molality, mol/kg - 5; Liquid	Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	ISOPERIBOL	8
POMD	3 5 6	Molar enthalpy of solution, kJ/mol ; Liquid	Solvent: Molality, mol/kg - 3; Liquid Molality, mol/kg - 5; Liquid	Pressure, kPa; Liquid Temperature, K; Liquid	Liquid	ISOPERIBOL	31
POMD	7 6	Molar enthalpy of solution, kJ/mol ; Liquid	Mole fraction - 7; Liquid Pressure, kPa; Liquid Temperature, K; Liquid		Liquid	ISOPERIBOL	1
POMD	8 6	Molar enthalpy of solution, kJ/mol ; Liquid	Mole fraction - 8; Liquid Pressure, kPa; Liquid Temperature, K; Liquid		Liquid	ISOPERIBOL	1

Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Enthalpy of solution of alpha- and beta-cyclodextrin in water and in some organic solvents

Belica, S.[Sylwia], Sadowska, M.[Monika], Stepniak, A.[Artur], Graca, A.[Anna], Palecz, B.[Barthomiej]

ABSTRACT