Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

ABSTRACT

The values of the solubility of evodiamine in chloroform, dichloromethane, acetone, ethyl acetate, 1-butanol, isopropanol, ethanol, methanol, ethyl ether, cyclohexane, n-pentane and n-hexane were measured at T = (283.2, 293.2, 303.2, 313.2, and 323.2) K. The solubility of evodiamine in all the organic solvents studied increases with the increase of the temperature. The experimental solubility values were correlated by a simplified thermodynamic equation and the modified Apelblat equation. The values of the dissolution enthalpy and entropy of evodiamine in all organic solvents were calculated using the van t Hoff equation. The findings showed that the dissolution process was endothermic and entropy-driven. These data of solubility can be used to guide the processes of extraction, purification in the industry.