ABSTRACT

The use of ionic liquids as a media for dissolving DNA holds great promise for the development of new base materials in electrochemistry. This paper reports the systematic study of the effect of two nucleic acid bases, uracil and adenine, on the ionicity of 1-alkyl-3-methylimidazolium acetates achieved by monitoring several thermodynamic and transport properties. Density, dynamic viscosity, speed of sound, refractive index and ionic conductivity of 1-ethyl-3-methylimidazolium acetate and 1-butyl-3-methylimidazolium acetate were studied as a function of temperature at atmospheric pressure. The thermal expansion coefficients and molar volumes of these ionic liquids were calculated from the experimental density values. The various properties of the binary mixtures 1-ethyl-3-methylimidazolium acetate with uracil or adenine, namely, their ionic conductivity, density and viscosity in the temperature range 298 K 343 K were determined as a function of the nucleobase content. Walden plots were determined and used to clarify the role of the nucleobases in the ionic liquids ionicity.

Compounds

#	Formula	Name
1	C5H5N5	6-amino-1H-purine
2	C4H4N2O2	2,4(1H,3H)-pyrimidinedione
3	C8H14N2O2	1-ethyl-3-methylimidazolium acetate
4	C10H18N2O2	1-butyl-3-methylimidazolium acetate

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	10
POMD	1	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	10
POMD	1	Electrical conductivity, S/m ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Alternating current cell with electrodes	6
POMD	2	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	10
POMD	2	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	10
POMD	2	Electrical conductivity, S/m ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Alternating current cell with electrodes	6
POMD	3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	13
POMD	3	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	13
POMD	3	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Linear variable-path acoustic interferometer	13
POMD	3	Refractive index (Na D-line) ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Standard Abbe refractometry	13
POMD	3	Electrical conductivity, S/m ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Alternating current cell with electrodes	9
POMD	4	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	13
POMD	4	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	13
POMD	4	Speed of sound, m/s ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Linear variable-path acoustic interferometer	13
POMD	4	Refractive index (Na D-line) ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Standard Abbe refractometry	13
POMD	4	Electrical conductivity, S/m ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid	Alternating current cell with electrodes	9
POMD	2 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Mass fraction - 3; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	70
POMD	2 3	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Mass fraction - 3; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	70
POMD	2 3	Electrical conductivity, S/m ; Liquid	Temperature, K; Liquid Mass fraction - 3; Liquid	Pressure, kPa; Liquid	Liquid	Alternating current cell with electrodes	42
POMD	1 3	Mass density, kg/m3 ; Liquid	Temperature, K; Liquid Mass fraction - 3; Liquid	Pressure, kPa; Liquid	Liquid	Vibrating tube method	60
POMD	1 3	Viscosity, Pa*s ; Liquid	Temperature, K; Liquid Mass fraction - 3; Liquid	Pressure, kPa; Liquid	Liquid	Capillary tube (Ostwald; Ubbelohde) method	60
POMD	1 3	Electrical conductivity, S/m ; Liquid	Temperature, K; Liquid Mass fraction - 3; Liquid	Pressure, kPa; Liquid	Liquid	Alternating current cell with electrodes	36

Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Nucleic acid bases in 1-alkyl-3-methylimidazolium acetate ionic liquids: A thermophysical and ionic conductivity analysis

Araujo, J. M. M., Pereiro, A. B., Alves, F., Marrucho, I. M., Rebelo, L. P. N.

ABSTRACT