Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Determination and correlation of the solubility for diosgenin in alcohols solvents

Chen, F.-x.[Fei-xiong], Zhao, M.-r.[Ming-rui], Liu, C.-C.[Chuo- Chuo], Peng, F.-f.[Fei-fei], Ren, B.-z.[Bao-zeng]
J. Chem. Thermodyn. 2012, 50, 1-6
ABSTRACT
Using a laser monitoring technique, the solubility data of diosgenin in ethanol, 1-propanol, 1-butanol, isobutyl alcohol, tert-butanol, 1-pentanol and iso-octyl alcohol were measured over the temperature range from (290.15 to 330.15) K at atmospheric pressure. Its corresponding (solid + liquid) equilibrium data will provide essential support for industrial design and further theoretical studies. From the experimental data, the solubility of diosgenin in ethanol, 1-propanol, 1-butanol, isobutyl alcohol, tert-butanol, 1-pentanol and iso-octyl alcohol were found to increase with increasing temperature and decrease with the increase of the polarity of the alcohols solvents. The Apelblat equation, the ideal model and the lamda-h equation were used to correlate the solubility data; the results showed that the three models mentioned above agreed well with the experimental data.
Compounds
# Formula Name
1 C27H42O3 Diosgenin
2 C2H6O ethanol
3 C3H8O propan-1-ol
4 C4H10O butan-1-ol
5 C4H10O 2-methyl-1-propanol
6 C4H10O 2-methylpropan-2-ol
7 C5H12O pentan-1-ol
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 2
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Visual
  • 15
  • POMD
  • 3
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Visual
  • 16
  • POMD
  • 4
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Visual
  • 17
  • POMD
  • 5
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Visual
  • 19
  • POMD
  • 6
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Visual
  • 17
  • POMD
  • 7
  • 1
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Visual
  • 19