ABSTRACT

(Solid + liquid) and (liquid + liquid) phase equilibria of binary mixtures containing various ionic liquid and erythromycin were studied. The solubility of erythromycin in 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl) imide, or 1-decyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, or trihexiltertadecilphosphonium chloride, or butyltrimethylammonium bis(trifluoromethylsulfonyl)imide, or methyltrioctylammonium bis(trifluoromethylsulfonyl)imide, or 1-butyl-1-methyl-pyrrolidinium bis(trifluoromethylsulfonyl) imide has been measured by a dynamic method, in a wide range of temperatures from (284 to 358) K, at atmospheric pressure. The activity coefficients of erythromycin in ionic liquids were calculated and their comparison with ideal solution was discussed. The experimental data were correlated successfully by means of the semi-empirical Grant equation.

Compounds

#	Formula	Name
1	C37H67NO13	erythromycin
2	C10H15F6N3O4S2	1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide
3	C16H27F6N3O4S2	1-decyl-3-methylimidazolium bis(trifluoromethylsulfonyl)amide
4	C32H68ClP	trihexyl(tetradecyl)phosphonium chloride
5	C9H18F6N2O4S2	butyltrimethylammonium bis(trifluoromethylsulfonyl)imide
6	C27H54F6N2O4S2	methyltrioctylammonium 1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide
7	C11H20F6N2O4S2	1-butyl-1-methylpyrrolidinium bis[(trifluoromethyl)sulfonyl]imide

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1 2	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	visual dynamic method	10
POMD	1 3	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	visual dynamic method	4
POMD	1 4	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	visual dynamic method	4
POMD	1 5	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	visual dynamic method	4
POMD	1 6	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	visual dynamic method	5
POMD	1 6	Mole fraction - 1 ; Liquid mixture 1	Temperature, K; Liquid mixture 1	Pressure, kPa; Liquid mixture 1	Liquid mixture 1 Liquid mixture 2	visual dynamic method	12
POMD	1 7	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	visual dynamic method	5

Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Solubility of erythromycin in ionic liquids

Manic, M. S.[Marina S.], Najdanovic-Visak, V.[Vesna]

ABSTRACT