The crystal structures of ephedrine hydrochloride and N-methylephedrine hydrochloride have been determined by X-ray crystallography. The molar enthalpies of dissolution of the two compounds with various molalities were measured at T = 298.15 K in distilled water by means of isoperibol solution-reaction calorimeter, respectively. According to the theory of Pitzer, the molar enthalpies of dissolution of the two compounds at infinite dilution, DsH1m , and Pitzer s parameters bo0PL MX ; bo1PL MX ; and CUL MX, were obtained. Then the values of apparent relative molar enthalpies oULP, hydration heat, and relative partial molar enthalpies of the two compounds oL2P were derived from the experimental results of the enthalpies of dissolution of the two compounds. Finally, the ionic radius of the cations can be calculated from the data of the corresponding effective volume of the cations.
Compounds
#
Formula
Name
1
C10H16ClNO
ephedrine hydrochloride
2
C11H18ClNO
(-)-N-methylephedrine hydrochloride
3
H2O
water
Datasets
The table above is generated from the ThermoML associated json file (link above).
POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied;
the numbers refer to the table of compounds on the left.