Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Solubility of climbazole and triclocarban in supercritical carbon dioxide: Measurement and correlation

Park, C. I.[Chan Ik], Shin, M. S.[Moon Sam], Kim, H.[Hwayong]
J. Chem. Thermodyn. 2009, 41, 1, 30-34
ABSTRACT
The supercritical technology has been considered as an appropriate alternative for separation of biomaterials from cosmetic, food, and pharmaceutical products. The solid solubility of biological compounds is the most important thermodynamic parameter in the supercritical extraction and purification. The equilibrium solubility of two biocides, climbazole, and triclocarban was measured in supercritical carbon dioxide with static method in the pressure range from (10 to 40) MPa and at temperatures equal to (313.2, 323.2, and 333.2) K. The experimental data were correlated by Peng Robinson equation of state and quasi-chemical nonrandom lattice fluid model.
Compounds
# Formula Name
1 CO2 carbon dioxide
2 C15H17ClN2O2 1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutanone
3 C13H9Cl3N2O N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 2
  • Vapor or sublimation pressure, kPa ; Gas
  • Temperature, K; Gas
  • Mole fraction - 2; Gas
  • Gas
  • Crystal - 2
  • Closed cell (Static) method
  • 24
  • POMD
  • 3
  • 1
  • Vapor or sublimation pressure, kPa ; Gas
  • Temperature, K; Gas
  • Mole fraction - 1; Gas
  • Gas
  • Crystal - 3
  • Closed cell (Static) method
  • 24