Thermodynamics Research Center / ThermoML | Journal of Chemical Thermodynamics

Experimental and computational thermochemistry of the dihydroxypyridine isomers

Morais, V. M. F.[Victor M. F.], Miranda, M. S.[Margarida S.], Matos, M. A. R.[M. Agostinha R.]
J. Chem. Thermodyn. 2006, 38, 4, 450-454
ABSTRACT
The standard (p? = 0.1 MPa) molar enthalpy of formation for crystalline 2,3-dihydroxypyridine was measured, at T = 298.15 K, by static bomb calorimetry and the standard molar enthalpy of sublimation, at T = 298.15 K, was obtained using Calvet microcalorimetry. These values were used to derive the standard molar enthalpy of formation of 2,3-dihydroxypyridine in gaseous phase, at T = 298.15 K, (263.9 +- 4.6) kJ Ae mol?1. Additionally, high-level density functional theory calculations using the B3LYP hybrid exchange-correlation energy functional with extended basis sets have been performed for all dihydroxypyridine isomers to determine the thermochemical order of stability of these systems. The agreement between experiment and theory for the 2,3-dihydroxypyridine isomer gives confidence to the estimates of the enthalpies of formation concerning the other five isomers. It is found that the enthalpic increment for the dihydroxy substitution of pyridine is equal to the sum of the respective enthalpic increment of the monosubstituted pyridines.
Compounds
# Formula Name
1 CO2 carbon dioxide
2 N2 nitrogen
3 H2O water
4 O2 oxygen
5 C5H5NO2 2,3-dihydroxypyridine
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 5
  • Mass density, kg/m3 ; Crystal
  • Temperature, K; Crystal
  • Pressure, kPa; Crystal
  • Crystal
  • mass and volume measurments
  • 1
  • POMD
  • 5
  • Molar enthalpy, kJ/mol ; Gas
  • Temperature, K; Gas
  • Pressure, kPa; Gas
  • Gas
  • "vacuum sublimation" drop microcalorimetric method
  • 1
  • RXND
  • 5
  • 1
  • 2
  • 3
  • 4
  • Specific internal energy of reaction at constant volume, J/g
  • Static bomb calorimetry
  • 1