Thermodynamics Research Center / ThermoML | Fluid Phase Equilibria

Recovery of flavonoids using novel biodegradable choline amino acids ionic liquids based ATPS

Gomez, Elena, Requejo, Patricia F., Tojo, Emilia, Macedo, Eugenia A.
Fluid Phase Equilib. 2019, 493, 1-9
ABSTRACT
In this work, different ionic liquids composed by choline as cation and amino acid as anion (CAAILs) have been synthetized and applied to establish aqueous two-phase systems (ATPS) with two phosphate salts. In order to understand the phase formation process of the ATPS, binodal curves, tie-lines and their respective tie-line lengths were determined at T = 298.15 K and atmospheric pressure. Besides, the tie-lines were fitted using Othmer-Tobias and Bancroft equations. Furthermore, with the aim to analyse the application of the studied ATPS in the recovery of flavonoids, partition coefficients of rutin and quercetin were calculated at T = 298.15 K and atmospheric pressure. Finally, the obtained results were compared with those found in literature.
Compounds
# Formula Name
1 K3O4P tripotassium phosphate
2 HK2O4P dipotassium hydrogen phosphate
3 C8H20N2O3 2-hydroxy-N,N,N-trimethylethanaminium L-alaninate
4 C7H18N2O3 2-hydroxy-N,N,N-trimethylethanaminium glycinate
5 C8H20N2O4 2-hydroxy-N,N,N-trimethylethanaminium L-serinate
6 H2O water
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 3
  • 1
  • 6
  • Mass fraction - 1 ; Liquid mixture 1
  • Mass fraction - 3; Liquid mixture 1
  • Temperature, K; Liquid mixture 1
  • Pressure, kPa; Liquid mixture 1
  • Liquid mixture 1
  • Liquid mixture 2
  • Titration method
  • 33
  • POMD
  • 3
  • 1
  • 6
  • Mass fraction - 1 ; Liquid mixture 1
  • Mass fraction - 3 ; Liquid mixture 2
  • Mass fraction - 1 ; Liquid mixture 2
  • Mass fraction - 3; Liquid mixture 1
  • Temperature, K; Liquid mixture 2
  • Pressure, kPa; Liquid mixture 2
  • Liquid mixture 1
  • Liquid mixture 2
  • OTHER
  • OTHER
  • OTHER
  • 4
  • POMD
  • 4
  • 1
  • 6
  • Mass fraction - 1 ; Liquid mixture 1
  • Mass fraction - 4; Liquid mixture 1
  • Temperature, K; Liquid mixture 1
  • Pressure, kPa; Liquid mixture 1
  • Liquid mixture 1
  • Liquid mixture 2
  • Titration method
  • 34
  • POMD
  • 4
  • 1
  • 6
  • Mass fraction - 1 ; Liquid mixture 1
  • Mass fraction - 4 ; Liquid mixture 2
  • Mass fraction - 1 ; Liquid mixture 2
  • Mass fraction - 4; Liquid mixture 1
  • Temperature, K; Liquid mixture 2
  • Pressure, kPa; Liquid mixture 2
  • Liquid mixture 1
  • Liquid mixture 2
  • OTHER
  • OTHER
  • OTHER
  • 5
  • POMD
  • 5
  • 1
  • 6
  • Mass fraction - 1 ; Liquid mixture 1
  • Mass fraction - 5; Liquid mixture 1
  • Temperature, K; Liquid mixture 1
  • Pressure, kPa; Liquid mixture 1
  • Liquid mixture 1
  • Liquid mixture 2
  • Titration method
  • 27
  • POMD
  • 5
  • 1
  • 6
  • Mass fraction - 1 ; Liquid mixture 1
  • Mass fraction - 5 ; Liquid mixture 2
  • Mass fraction - 1 ; Liquid mixture 2
  • Mass fraction - 5; Liquid mixture 1
  • Temperature, K; Liquid mixture 2
  • Pressure, kPa; Liquid mixture 2
  • Liquid mixture 1
  • Liquid mixture 2
  • OTHER
  • OTHER
  • OTHER
  • 4
  • POMD
  • 3
  • 2
  • 6
  • Mass fraction - 2 ; Liquid mixture 1
  • Mass fraction - 3; Liquid mixture 1
  • Temperature, K; Liquid mixture 1
  • Pressure, kPa; Liquid mixture 1
  • Liquid mixture 1
  • Liquid mixture 2
  • Titration method
  • 34
  • POMD
  • 3
  • 2
  • 6
  • Mass fraction - 2 ; Liquid mixture 1
  • Mass fraction - 3 ; Liquid mixture 2
  • Mass fraction - 2 ; Liquid mixture 2
  • Mass fraction - 3; Liquid mixture 1
  • Temperature, K; Liquid mixture 2
  • Pressure, kPa; Liquid mixture 2
  • Liquid mixture 1
  • Liquid mixture 2
  • OTHER
  • OTHER
  • OTHER
  • 4
  • POMD
  • 4
  • 2
  • 6
  • Mass fraction - 2 ; Liquid mixture 1
  • Mass fraction - 4; Liquid mixture 1
  • Temperature, K; Liquid mixture 1
  • Pressure, kPa; Liquid mixture 1
  • Liquid mixture 1
  • Liquid mixture 2
  • Titration method
  • 33
  • POMD
  • 4
  • 2
  • 6
  • Mass fraction - 2 ; Liquid mixture 1
  • Mass fraction - 4 ; Liquid mixture 2
  • Mass fraction - 2 ; Liquid mixture 2
  • Mass fraction - 4; Liquid mixture 1
  • Temperature, K; Liquid mixture 2
  • Pressure, kPa; Liquid mixture 2
  • Liquid mixture 1
  • Liquid mixture 2
  • OTHER
  • OTHER
  • OTHER
  • 4
  • POMD
  • 5
  • 2
  • 6
  • Mass fraction - 2 ; Liquid mixture 1
  • Mass fraction - 5; Liquid mixture 1
  • Temperature, K; Liquid mixture 1
  • Pressure, kPa; Liquid mixture 1
  • Liquid mixture 1
  • Liquid mixture 2
  • Titration method
  • 29
  • POMD
  • 5
  • 2
  • 6
  • Mass fraction - 2 ; Liquid mixture 1
  • Mass fraction - 5 ; Liquid mixture 2
  • Mass fraction - 2 ; Liquid mixture 2
  • Mass fraction - 5; Liquid mixture 1
  • Temperature, K; Liquid mixture 2
  • Pressure, kPa; Liquid mixture 2
  • Liquid mixture 1
  • Liquid mixture 2
  • OTHER
  • OTHER
  • OTHER
  • 4