Thermodynamics Research Center / ThermoML | Fluid Phase Equilibria

Thermodynamic analysis and correlation of solubility of disodium 5'-guanylate heptahydrate in aqueous ethanol mixtures

Liu, B.[Baoshu], Sun, H.[Hua], Wang, J.[Jingkang], Yin, Q.[Qiuxiang]
Fluid Phase Equilib. 2014, 370, 58-64
ABSTRACT
The solubility of disodium 5 -guanylate heptahydrate (5 -GMPNa2) in water-ethanol binary solvent mixtures was measured at temperatures ranging from 278.15 K to 323.15 K using a dynamic method. The solubility data were correlated by the Apelblat equation, the Combined Nearly Ideal Binary Solvent/Redlich-Kister (CNIBS/R-K) equation and the modified Jouyban-Acree equation, respectively. Results showed that a reasonable match with experimental data is obtained from the Apelblat equation and CNIBS/R-K equation, while the modified Jouyban-Acree equation contains parameters including both solvent composition and temperature. The thermodynamic functions Gibbs free energy, enthalpy, and entropy of solution were also calculated based on solubility data of 5'-GMPNa2 determined in binary water + ethanol solvent mixtures by using van't Hoff equation. The dissolving process is endothermic and the dissolution driving force converts from enthalpy-driving to entropy-driving.
Compounds
# Formula Name
1 C10H26N5Na2O15P disodium 5'-guanylate heptahydrate
2 C2H6O ethanol
3 H2O water
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 2
  • 3
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mole fraction - 2; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Titration method
  • 70