Thermodynamics Research Center / ThermoML | Fluid Phase Equilibria

Solubility of fluphenazine decanoate in aqueous mixtures of polyethylene glycols 400 and 600 at various temperatures

Jouyban, A.[Abolghasem], Martinez, F.[Fleming], Panahi-Azar, V.[Vahid]
Fluid Phase Equilib. 2014, 368, 58-64
ABSTRACT
The solubility of fluphenazine decanoate (FD) in aqueous binary mixtures of polyethylene glycols 400 (PEG 400) and 600 (PEG 600) at 298.0 to 318.0 K and atmospheric pressure along with some thermodynamic properties are reported. The previously trained version of the Jouyban-Acree model for PEG 400 + water, a recently proposed general cosolvency model employing partial solubility parameters, and a combination of the model with van't Hoff equation were used to predict the solubility of FD in PEG 400 + water and PEG 600 + water at different temperatures. The results show that the Jouyban-Acree model can be used for solubility prediction of FD in aqueous mixtures of PEG 400 and PEG 600 at different temperatures. Densities of solute free aqueous mixtures of PEG 400 and PEG 600 along with their FD-saturated solutions are also reported.
Compounds
# Formula Name
1 C32H44F3N3O2S decanoic acid, 2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl ester
2 H2O water
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 2
  • Mass density, kg/m3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Pycnometric method
  • 5
  • POMD
  • 1
  • 2
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • UV-Vis spectrophotometer
  • 5
  • POMD
  • 1
  • 2
  • Mass density, kg/m3 ; Liquid
  • Temperature, K; Liquid
  • Mole fraction - 1; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Pycnometric method
  • 5