Thermodynamics Research Center / ThermoML | Fluid Phase Equilibria

Solubility of glycine in binary system of ethanol + water solvent mixtures: Experimental data and thermodynamic modeling

Cao, Z.[Zheng], Hu, Y.[Yonghong], Li, J.[Jiaojiao], Kai, Y.[Yumei], Yang, W.[Wenge]
Fluid Phase Equilib. 2013, 360, 156-160
ABSTRACT
The solubility of glycine in different compositions of ethanol - water binary solvent mixtures was measured with the temperature ranging from 278.15 K to 328.15 K at intervals of 5.00 K by employing an analytical stirred-flask method. The solubility data were fitted using the modified Apelblat equation and the combined nearly ideal binary solvent/Redlich-Kister (CNIBS/R-K) equation, respectively. The modified Apelblat equation was found to regress the solubility data much better than the other two equations. The Van't Hoff equation was used to calculate the apparent molar enthalpy and the apparent molar entropy of solution in the binary mixture solvent system, the dissolving process was endothermic and entropy-driving. The experiment results and correlation models could be used as essential data in the purification of glycine.
Compounds
# Formula Name
1 C2H5NO2 2-aminoacetic acid
2 C2H6O ethanol
3 H2O water
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 2
  • 3
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Solvent: Mass fraction - 2; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Mass after drying
  • 77
  • POMD
  • 1
  • 3
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Mass after drying
  • 11
  • POMD
  • 1
  • 2
  • Mole fraction - 1 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 1
  • Mass after drying
  • 11