Thermodynamics Research Center / ThermoML | Fluid Phase Equilibria

Measurement of solubility of erythromycin acetone solvate in aqueous acetone solution between 298K and 323K

Wang, Z.[Zhanzhong], Dang, L.[Leping]
Fluid Phase Equilib. 2009, 276, 2, 94-98
ABSTRACT
Using a laser monitoring observation technique, the solubility of erythromycin acetone solvate in binary acetone + water solvent mixtures was measured by a synthetic method at temperatures ranging from 298.00 K to 323.00 K and at atmosphere pressure. The results of these measurements were correlated by the combined nearly ideal binary solvent CNIBS/Redlich-Kister equation and the modified Apelblat equation, respectively. For the solubility data studied, the CNIBS/Redlich-Kister equation was found to provide a more accurate mathematical representation of the experimental data.
Compounds
# Formula Name
1 C3H6O acetone
2 H2O water
3 C40H73N3O12 erythromycin, 9-[(1-methylethylidene)hydrazone]
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 2
  • 3
  • Mole fraction - 3 ; Liquid
  • Solvent: Mole fraction - 2; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 3
  • OTHER:UFactor:16:sMethod:synthetic method
  • 48
  • POMD
  • 1
  • 3
  • Mole fraction - 3 ; Liquid
  • Temperature, K; Liquid
  • Pressure, kPa; Liquid
  • Liquid
  • Crystal - 3
  • OTHER:UFactor:16:sMethod:synthetic method
  • 6