Thermodynamics Research Center / ThermoML | Fluid Phase Equilibria

Solubility of iodopropynyl butylcarbamate in supercritical carbon dioxide

Shin, M. S.[Moon Sam], Kim, H.[Hwayong]
Fluid Phase Equilib. 2008, 270, 1-2, 45-49
ABSTRACT
Supercritical carbon dioxide has been considered an appropriate alternative for extraction and purification process of cosmetics, pharmaceuticals, food supplements and natural products. Solubility information of biological compounds is essential for choosing supercritical fluid (SCF) processes. The solubility of iodopropynyl butylcarbamate (IPBC), a fungicide and anti-dandruff agent, was measured in supercritical carbon dioxide with a high pressure apparatus equipped with a variable volume view cell at 313.15, 323.15, and 333.15K and at pressure between 80 and 35MPa. The experimental data were correlated well with Peng Robinson equation of state (PR EOS) and quasi-chemical nonrandom lattice fluid model.
Compounds
# Formula Name
1 CO2 carbon dioxide
2 C8H12INO2 iodopropynyl butylcarbamate
3 C14H10 phenanthrene
Datasets
The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type Compound-# Property Variable Constraint Phase Method #Points
  • POMD
  • 1
  • 2
  • Mole fraction - 2 ; Fluid (supercritical or subcritical phases)
  • Temperature, K; Fluid (supercritical or subcritical phases)
  • Pressure, kPa; Fluid (supercritical or subcritical phases)
  • Fluid (supercritical or subcritical phases)
  • Crystal - 2
  • Varible volume high-pressure cell
  • 27
  • POMD
  • 3
  • 1
  • Mole fraction - 1 ; Fluid (supercritical or subcritical phases)
  • Pressure, kPa; Fluid (supercritical or subcritical phases)
  • Temperature, K; Fluid (supercritical or subcritical phases)
  • Fluid (supercritical or subcritical phases)
  • Crystal - 3
  • Once cloud point was found, solubility was calculated using the known amount of solid loaded into vessel along with the amount of CO2 present.
  • 11