ABSTRACT

The solubility of baicalein in methanol, ethanol, n-propanol, propan-2-ol, n-butanol, isobutyl alcohol, 1,3-propanediol, and ethyl acetate was measured from (287 to 323) K at atmospheric pressure using high-performance liquid chromatography analysis. Its corresponding (solid + liquid) equilibrium data should provide essential support for the purification of baicalein. The solubility data were correlated by the modified Apelblat equation and the van t Hoff equation. The solubility data indicated that ethyl acetate might be the best choice for purification of baicalein among these solvents. The correlated results showed that the two equations were both in good agreement with the experimental values, but the correlation of the modified Apelblat equation had smaller deviations than those of the van t Hoff equation.

Compounds

#	Formula	Name
1	C15H10O5	baicalein
2	CH4O	methanol
3	C2H6O	ethanol
4	C3H8O	propan-1-ol
5	C3H8O	propan-2-ol
6	C4H10O	butan-1-ol
7	C4H10O	2-methyl-1-propanol
8	C3H8O2	propan-1,3-diol
9	C4H8O2	ethyl acetate

Datasets

The table above is generated from the ThermoML associated json file (link above). POMD and RXND refer to PureOrMixture and Reaction Datasets. The compound numbers are included in properties, variables, and phases, if specificied; the numbers refer to the table of compounds on the left.
Type	Compound-#	Property	Variable	Constraint	Phase	Method	#Points
POMD	1	Triple point temperature, K ; Crystal			Crystal Liquid Air at 1 atmosphere	VISOBS	1
POMD	2 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	3 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	4 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	5 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	6 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	7 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	1 8	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10
POMD	9 1	Mole fraction - 1 ; Liquid	Temperature, K; Liquid	Pressure, kPa; Liquid	Liquid Crystal - 1	Chromatography	10

Thermodynamics Research Center / ThermoML | International Journal of Thermophysics

Solubility of Baicalein in Different Solvents from (287 to 323) K

Wu, J.[Jianguo], Gu, L.[Liwen], Wang, H.[Haining], Tao, L.[Lijing], Wang, X.[Xinfeng]

ABSTRACT