2
0
2009
mat
kab
0
journal
Original
Matsuda, H.[Hiroyuki]
Kaburagi, K.[Kenta]
Matsumoto, S.[Sho]
Kurihara, K.[Kiyofumi]
Tochigi, K.[Katsumi]
Tomono, K.[Kazuo]
J. Chem. Eng. Data
2009
2020-09-29
Solubilities of Salicylic Acid in Pure Solvents and Binary Mixtures Containing Cosolvent
The solubility of salicylic acid in water, methanol, ethanol, ethyl acetate, polyethylene glycol (PEG) 300, and 1,4-dioxane and in various binary solvent mixtures, methanol + water, ethanol + water, ethanol + ethyl acetate, PEG 300 + water, and 1,4-dioxane + water, were determined using high-performance liquid chromatography (HPLC). The experimental solubility data were correlated by two local composition models: modified Wilson and nonrandom two-liquid (NRTL) 1.
10.1021/je800475d
2
54
480-484
1
InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
YGSDEFSMJLZEOE-UHFFFAOYSA-N
2-hydroxybenzoic acid
benzoic acid, 2-hydroxy-
o-hydroxybenzoic acid
phenol-2-carboxylic acid
salicylic acid
C7H6O3
1
Commercial source
1
99.5
3
Stated by supplier
2
InChI=1S/CH4O/c1-2/h2H,1H3
OKKJLVBELUTLKV-UHFFFAOYSA-N
methanol
methyl alcohol
CH4O
1
Commercial source
1
99.8
3
Stated by supplier
3
InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N
ethanol
ethyl alcohol
C2H6O
1
Commercial source
1
99.5
3
Stated by supplier
4
InChI=1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
XEKOWRVHYACXOJ-UHFFFAOYSA-N
ethyl acetate
ethyl ethanoate
C4H8O2
1
Commercial source
1
99.5
3
Stated by supplier
5
InChI=1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2
RYHBNJHYFVUHQT-UHFFFAOYSA-N
1,4-dioxane
1,4-dioxacyclohexane
dioxane
p-dioxane
tetrahydro-1,4-dioxin
C4H8O2
1
Commercial source
1
99
2
Stated by supplier
6
InChI=1S/H2O/h1H2
XLYOFNOQVPJJNP-UHFFFAOYSA-N
water
H2O
1
Commercial source
1
Fractional distillation
2
99.9
3
Estimated by the compiler
1
2
1
1
1
6
1
Principal objective of the work
VN
TRC
2/24/2009
1
Mole fraction
UV-vis detector
1
Liquid
Direct value, X
2
6
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
2
Temperature, K
Liquid
298.15
5
1
Solvent: Mole fraction
2
Liquid
1
0
2
1
0.0003
1
1
0.0001
1
0.0903
3
1
0.0006
1
1
0.0001
1
0.1942
4
1
0.0021
2
1
0.0003
1
0.3599
4
1
0.0113
3
1
0.0014
2
3
1
1
1
6
1
Principal objective of the work
VN
TRC
2/24/2009
1
Mole fraction
UV-vis detector
1
Liquid
Direct value, X
3
6
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
2
Temperature, K
Liquid
298.15
5
1
Solvent: Mole fraction
3
Liquid
1
0
2
1
0.0003
1
1
0.0001
1
0.0329
3
1
0.0004
1
1
0.0001
1
0.0731
3
1
0.0007
1
1
0.0002
1
0.1179
4
1
0.002
2
1
0.0006
1
0.1707
4
1
0.0063
2
1
0.0012
1
0.2348
4
1
0.0161
3
1
0.002
1
0.2734
4
1
0.026
3
1
0.0032
1
0.2899
4
1
0.0294
3
1
0.0037
1
0.3183
4
1
0.0342
3
1
0.0043
1
0.3665
4
1
0.0449
3
1
0.0056
1
0.4159
4
1
0.0541
3
1
0.0067
1
0.4774
4
1
0.0666
3
1
0.0083
1
0.5487
4
1
0.0781
3
1
0.0097
1
0.6314
4
1
0.0981
3
1
0.0122
1
0.7407
4
1
0.1178
4
1
0.017
1
0.8457
4
1
0.1295
4
1
0.0286
1
1
5
1
0.145
4
1
0.018
3
3
1
1
1
4
1
Principal objective of the work
VN
TRC
2/24/2009
1
Mole fraction
UV-vis detector
1
Liquid
Direct value, X
3
4
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
2
Temperature, K
Liquid
298.15
5
1
Solvent: Mole fraction
3
Liquid
1
0
2
1
0.1383
4
1
0.0172
1
0.1613
4
1
0.1653
4
1
0.0205
1
0.2991
4
1
0.1767
4
1
0.0219
1
0.4201
4
1
0.181
4
1
0.0225
1
0.5262
4
1
0.1808
4
1
0.0224
1
0.6277
4
1
0.1839
4
1
0.0228
1
0.7134
4
1
0.1738
4
1
0.0216
1
0.7947
4
1
0.1754
4
1
0.0218
1
0.8701
4
1
0.1616
4
1
0.035
1
0.9389
4
1
0.1446
4
1
0.018
1
1
5
1
0.145
4
1
0.018
4
1
1
5
1
6
1
Principal objective of the work
VN
TRC
2/24/2009
1
Mole fraction
UV-vis detector
1
Liquid
Direct value, X
5
6
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
2
Temperature, K
Liquid
298.15
5
1
Solvent: Mole fraction
5
Liquid
1
0
2
1
0.0003
1
1
0.0001
1
0.0238
3
1
0.0008
1
1
0.0001
1
0.0506
3
1
0.0018
2
1
0.0002
1
0.0832
3
1
0.0066
2
1
0.0008
1
0.1246
4
1
0.0221
3
1
0.0028
1
0.173
4
1
0.0436
3
1
0.0066
1
0.2394
4
1
0.0784
3
1
0.0097
1
0.3294
4
1
0.1212
4
1
0.0151
1
0.4572
4
1
0.1616
4
1
0.032
1
0.6573
4
1
0.2173
4
1
0.027
1
1
5
1
0.261
4
1
0.0324