2
0
2010
li
wan
1
journal
Original
Li, Q.-S.[Qun-Sheng]
Wang, D.-W.[Da-Wei]
Yi, Z.-M.[Zheng-Ming]
J. Chem. Eng. Data
2010
2020-09-29
Solubility of Sulpiride in Pure Organic Solvents between (278 and 333) K
The solubility of sulpiride in organic solvents of acetone, N-methylpyrrolidone (NMP), ethanol, tetrahydropyran (THF), N,N-dimethylformamide (DMF), and methanol between (278 and 328) K was measured using a laser monitoring observation technique. Results of these measurements were correlated with a semiempirical equation. For the seven solvents studied, the data are fitted well with a semiempirical equation.
10.1021/je1002016
9
55
4066-4067
1
InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)
BGRJTUBHPOOWDU-UHFFFAOYSA-N
N-((1-ethylpyrrolidin-2-yl)methyl)-2-methoxy-5-sulfamoylbenzamide
sulpiride
C15H23N3O4S
1
Commercial source
1
99.7
3
HPLC
2
InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N
ethanol
ethyl alcohol
C2H6O
1
Commercial source
3
InChI=1S/C3H6O/c1-3(2)4/h1-2H3
CSCPPACGZOOCGX-UHFFFAOYSA-N
acetone
2-propanone
dimethyl ketone
propan-2-one
propanone
pyroacetic ether
C3H6O
1
Commercial source
4
InChI=1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
ZMXDDKWLCZADIW-UHFFFAOYSA-N
dimethylformamide
DMF
DMFA
N,N-dimethylformamide
N,N-dimethylmethanamide
dimethylformamide (DMF)
C3H7NO
1
Commercial source
5
InChI=1S/C4H8O/c1-2-4-5-3-1/h1-4H2
WYURNTSHIVDZCO-UHFFFAOYSA-N
tetrahydrofuran
1,4-epoxybutane
THF
oxacyclopentane
oxolane
tetramethylene oxide
C4H8O
1
Commercial source
6
InChI=1S/CH4O/c1-2/h2H,1H3
OKKJLVBELUTLKV-UHFFFAOYSA-N
methanol
methyl alcohol
CH4O
1
Commercial source
7
InChI=1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
SECXISVLQFMRJM-UHFFFAOYSA-N
N-methylpyrrolidone
1-methyl-2-pyrrolidinone
1-methyl-2-pyrrolidone
1-methyl-5-pyrrolidinone
1-methylazacyclopentan-2-one
1-methylpyrrolidin-2-one
1-methylpyrrolidone
N-methyl-.alpha.-pyrrolidinone
N-methyl-.alpha.-pyrrolidone
N-methyl-.gamma.-butyrolactam
N-methyl-2-pyrrolidinone
N-methyl-2-pyrrolidone
N-methylpyrrolidin-2-one
NMP
C5H9NO
1
Commercial source
1
2
1
1
1
Principal objective of the work
KNA
TRC
9/27/2010
1
Mole fraction
monitored by a laser beam
1
Liquid
Direct value, X
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
1
Temperature, K
Liquid
1
288.76
5
1
0.00045
4
1
1.95e-05
1
294.01
5
1
0.000576
4
1
2.5e-05
1
298.74
5
1
0.0007638
4
1
3.31e-05
1
303.65
5
1
0.0009904
4
1
4.29e-05
1
308
5
1
0.00123
4
1
5.3e-05
1
313.4
5
1
0.001561
4
1
6.8e-05
1
318.2
5
1
0.002019
4
1
8.7e-05
1
324
5
1
0.002687
4
1
0.000116
1
328.1
5
1
0.003429
4
1
0.000149
1
332.7
5
1
0.004334
4
1
0.000187
2
3
1
1
1
Principal objective of the work
KNA
TRC
9/27/2010
1
Mole fraction
monitored by a laser beam
1
Liquid
Direct value, X
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
1
Temperature, K
Liquid
1
278.25
5
1
0.0009696
4
1
4.1e-05
1
283.3
5
1
0.001229
4
1
5.2e-05
1
287.85
5
1
0.00142
4
1
6e-05
1
293.5
5
1
0.001757
4
1
7.4e-05
1
298.25
5
1
0.002097
4
1
8.8e-05
1
303.05
5
1
0.002499
4
1
0.000105
1
308
5
1
0.003003
4
1
0.000126
1
313.5
5
1
0.003565
4
1
0.00015
1
318.55
5
1
0.004346
4
1
0.000183
1
323.45
5
1
0.005213
4
1
0.000219
3
4
1
1
1
Principal objective of the work
KNA
TRC
9/27/2010
1
Mole fraction
monitored by a laser beam
1
Liquid
Direct value, X
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
1
Temperature, K
Liquid
1
277.95
5
1
0.03884
4
1
0.00161
1
283.15
5
1
0.04366
4
1
0.00181
1
288.3
5
1
0.04878
4
1
0.00202
1
293.05
5
1
0.05376
4
1
0.00223
1
297.95
5
1
0.05931
4
1
0.00246
1
303
5
1
0.06504
4
1
0.00269
1
308.03
5
1
0.07165
4
1
0.00297
1
313.13
5
1
0.07874
4
1
0.00326
1
318.28
5
1
0.08643
4
1
0.00359
1
323.05
5
1
0.09444
4
1
0.00392
1
327.85
5
1
0.1035
4
1
0.0043
1
333.25
5
1
0.111
4
1
0.0046
4
5
1
1
1
Principal objective of the work
KNA
TRC
9/27/2010
1
Mole fraction
monitored by a laser beam
1
Liquid
Direct value, X
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
1
Temperature, K
Liquid
1
282.95
5
1
0.001088
4
1
4.5e-05
1
288.3
5
1
0.001373
4
1
5.7e-05
1
293.25
5
1
0.001775
4
1
7.4e-05
1
298.15
5
1
0.002244
4
1
9.3e-05
1
303.05
5
1
0.002744
4
1
0.000114
1
308.05
5
1
0.003326
4
1
0.000138
1
313.05
5
1
0.003972
4
1
0.000165
1
318.25
5
1
0.004825
4
1
0.0002
1
323.2
5
1
0.005827
4
1
0.000241
1
328.25
5
1
0.006941
4
1
0.000287
1
333.05
5
1
0.008305
4
1
0.000344
5
6
1
1
1
Principal objective of the work
KNA
TRC
9/27/2010
1
Mole fraction
monitored by a laser beam
1
Liquid
Direct value, X
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
1
Temperature, K
Liquid
1
278.18
5
1
0.0008554
4
1
3.96e-05
1
283.27
5
1
0.001115
4
1
5.2e-05
1
288.2
5
1
0.001417
4
1
6.6e-05
1
293.45
5
1
0.001831
4
1
8.5e-05
1
298.55
5
1
0.002209
4
1
0.000102
1
303.2
5
1
0.002764
4
1
0.000128
1
308.21
5
1
0.003496
4
1
0.000162
1
313.19
5
1
0.004574
4
1
0.000212
1
318.26
5
1
0.005678
4
1
0.000262
1
323.17
5
1
0.007039
4
1
0.000326
1
328.28
5
1
0.008932
4
1
0.000413
1
333.37
5
1
0.01076
4
1
0.0005
6
7
1
1
1
Principal objective of the work
KNA
TRC
9/27/2010
1
Mole fraction
monitored by a laser beam
1
Liquid
Direct value, X
1
Data file compiler
Propagation of evaluated standard uncertainties
95
Liquid
Crystal
1
1
Pressure, kPa
Liquid
101
3
1
Temperature, K
Liquid
1
283.68
5
1
0.08099
4
1
0.00331
1
288.5
5
1
0.08742
4
1
0.00357
1
293.85
5
1
0.09881
4
1
0.00404
1
298.75
5
1
0.1106
4
1
0.0045
1
303.2
5
1
0.1187
4
1
0.0049
1
308.5
5
1
0.1235
4
1
0.005
1
313.5
5
1
0.1334
4
1
0.0055
1
318.5
5
1
0.1404
4
1
0.0057